Where to Rest

The 5 best places to stay in Irvine Health and Science Complex (2026)

Ranked by real guest ratings across Irvine Health and Science Complex — only places with a solid number of reviews qualify.

  1. 1
    Hotel
    Courtyard by Marriott Irvine Spectrum★★★
    7955 Irvine Center Dr, Irvine, CA 92618
    ★ 4.5 (1261)
  2. 2
    Marriott Irvine Spectrum, Hotel in Irvine Health and Science ComplexHotel
    Marriott Irvine Spectrum★★★
    7905 Irvine Center Dr, Irvine, CA 92618
    ★ 4.4 (1152)
  3. 3
    DoubleTree by Hilton Hotel Irvine - Spectrum, Hotel in Irvine Health and Science ComplexHotel
    DoubleTree by Hilton Hotel Irvine - Spectrum★★★
    90 Pacifica, Irvine, CA 92618
    ★ 4.3 (1653)
  4. 4
    Sonesta Simply Suites Irvine Spectrum, Hotel in Irvine Health and Science ComplexHotel
    Sonesta Simply Suites Irvine Spectrum★★★
    16150 Sand Canyon Ave, Irvine, CA 92618
    ★ 3.9 (515)
  5. 5
    Extended Stay America Suites- Orange County - Irvine Spectrum, Aparthotel in Irvine Health and Science ComplexAparthotel
    Extended Stay America Suites- Orange County - Irvine Spectrum★★★
    30 Technology Dr W, Irvine, CA 92618
    ★ 3.4 (972)

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