Where to Rest

The 10 best places to stay in Saint Charles

Ranked by real guest ratings across Saint Charles — only places with a solid number of reviews qualify.

Compare live availability and prices for Saint Charles across our booking partner. We may earn a commission — it costs you nothing extra.

Check live prices in Saint Charles
  1. 1
    Camp Mill Pond, Guesthouse in Saint CharlesGuesthouse
    Camp Mill Pond
    305 Morgan St, St Charles, MO 63301
    ★ 5.0 (49)moderate
    Breakfast
    Check live prices · mid-range
  2. 2
    Le Velo Inn, Hotel in Saint CharlesHotel
    Le Velo Inn
    1425 N 2nd St, St Charles, MO 63301
    ★ 5.0 (21)
    Check live prices
  3. 3
    Drury Plaza Hotel St. Louis St. Charles, Hotel in Saint CharlesHotel
    Drury Plaza Hotel St. Louis St. Charles★★★
    380 Mulholland Dr, St Charles, MO 63303
    ★ 4.8 (1375)
    Check live prices
  4. 4
    Boone's Lick Trail Inn, Hotel in Saint CharlesHotel
    Boone's Lick Trail Inn
    1000 S Main St, St Charles, MO 63301
    ★ 4.7 (51)moderate
    BreakfastPet friendly
    Check live prices · mid-range
  5. 5
    Inn Frenchtown Bed and Breakfast, Bed & Breakfast in Saint CharlesBed & Breakfast
    Inn Frenchtown Bed and Breakfast
    1101 N 3rd St, St Charles, MO 63301
    ★ 4.7 (40)
    Breakfast
    Check live prices
  6. 6
    Boone's Colonial Inn, Hotel in Saint CharlesHotel
    Boone's Colonial Inn
    322 S Main St, St Charles, MO 63301
    ★ 4.5 (41)moderate
    BreakfastPet friendly
    Check live prices · mid-range
  7. 7
    Embassy Suites by Hilton St. Louis St. Charles, Hotel in Saint CharlesHotel
    Embassy Suites by Hilton St. Louis St. Charles★★★
    Two Convention Center Blvd, St Charles, MO 63303
    ★ 4.4 (3075)
    Check live prices
  8. 8
    Country Inn & Suites by Radisson, St. Charles Historic District, Hotel in Saint CharlesHotel
    Country Inn & Suites by Radisson, St. Charles Historic District
    1190 S Main St, St Charles, MO 63301
    ★ 4.4 (1090)
    Check live prices
  9. 9
    Extended Stay America - St. Louis - Earth City, Hotel in Saint CharlesHotel
    Extended Stay America - St. Louis - Earth City
    3125 Rider Trl S, Earth City
    ★ 4.3 (1319)
    Check live prices
  10. 10
    Ameristar Casino Resort Spa St. Charles, Hotel in Saint CharlesHotel
    Ameristar Casino Resort Spa St. Charles★★★★
    1 Ameristar Blvd, St Charles, MO 63301
    ★ 4.2 (14771)
    Check live prices

See all places to stay in Saint Charles →