The 6 best places to stay in Seneca (2026)

Ranked by real guest ratings across Seneca — only places with a solid number of reviews qualify.

1. 1
   Hotel

   Hampton Inn & Suites Seneca-Clemson Area★★★

   1011 E North 1st St, Seneca, SC 29678

   ★ 4.4 (597)
2. 2
   Hotel

   Fairfield by Marriott Inn & Suites Seneca Clemson Univ Area

   800 Bypass, US-123, Seneca, SC 29678

   ★ 4.3 (201)
3. 3
   Hotel

   Best Western - Seneca★★★

   511 Bypass Highway 123

   ★ 4.1 (432)
4. 4
   Motel

   Executive Inn of seneca★★

   299 ByPass 123, Seneca, SC 29678

   ★ 3.7 (77)
5. 5
   Hotel

   Days Inn by Wyndham Seneca / Clemson Area★★

   11015 N Radio Station Rd, Seneca, SC 29678

   ★ 3.6 (557)
6. 6
   Hotel

   Best Way Inn★★

   320 ByPass 123, Seneca, SC 29678

   ★ 3.5 (155)

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